TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
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چکیده
منابع مشابه
TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
The receptor for advanced glycation end products (RAGE) is thought to be involved in the pathogenesis of a broad range of inflammatory, degenerative and hyperproliferative diseases. It binds to diverse ligands and activates multiple intracellular signaling pathways. Despite these pivotal functions, molecular events just downstream of ligand-activated RAGE have been surprisingly unknown. Here we...
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Acknowledgements I would like to start by thanking Prof. Meir Edelman and Dr. Vladimir Sobolev for their guidance and the high level of scientific independence they trusted in me. A different posture would not have permitted my full development as a free thinker. I would like to thank Professors Ron Unger and Amnon Horovitz for their valuable comments throughout this work as assigned readers of...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0023132